RESUMO
Cerebral ganglioneuroblastoma is an embryonal tumor of the central nervous system, which has been rarely encountered into the spinal cord. The standard treatment for ganglioneuroblastoma is complete surgical excision. A 15-year old boy was presented with cord compression. Magnetic resonance imaging revealed an intradural and intramedullar enhancing lesion over T2 spine. A histomorphological diagnosis was made in the presence of immature small round cells admixed with a good number of ganglion cells. The morphological diagnosis was verified by immunohistochemistry. This is the first reported case of compressive myelopathy in the thoracic region of the spine.
Assuntos
Adolescente , Ganglioneuroblastoma/diagnóstico , Ganglioneuroblastoma/epidemiologia , Ganglioneuroblastoma/cirurgia , Humanos , Masculino , Neoplasias da Medula Espinal/diagnóstico , Neoplasias da Medula Espinal/epidemiologia , Neoplasias da Medula Espinal/cirurgia , Vértebras Torácicas/patologiaRESUMO
Endovascular papillary angioendothelioma (EPA) is a rare vascular tumor of low grade malignancy, encountered primarily in children. However some cases have also been reported in adults. A sixty year old female with EPA is described here. She presented with a swelling in the neck. Total surgical excision was performed. Histomorphology revealed anastomosing lymphatic channels showing intraluminal papillary fronds with hyaline vascular cores and hobnailing of endothelial cells. A diagnosis of EPA was made based on this picture. This tumor is recurrent and nodal metastasis has been reported in some cases.
Assuntos
Diagnóstico Diferencial , Feminino , Neoplasias de Cabeça e Pescoço/diagnóstico , Hemangioendotelioma/diagnóstico , Humanos , Pessoa de Meia-Idade , Pescoço/patologiaRESUMO
Haemangioblastoma is a rare benign vascular tumor commonly seen in the cerebellum. There is a striking histologic similarity between cellular variant of haemangioblastoma and metastatic renal cell carcinoma. We present a case of haemangioblastoma in a 32-year-old male. Histology revealed a highly vascular tumor composed of clear cells in a lobular arrangement.
Assuntos
Adulto , Carcinoma de Células Renais/diagnóstico , Neoplasias Cerebelares/diagnóstico , Cerebelo/patologia , Diagnóstico Diferencial , Hemangioblastoma/diagnóstico , Humanos , MasculinoRESUMO
Plasma cell leukemia (PCL) is a rare type of plasma cell dyscrasia. It is diagnosed when circulating plasma cells (PC) are more than 20%. We present a case of PCL in a 62-year-old female. Peripheral smear revealed more than 80% atypical vacuolated plasma cells (Mott cells) almost mimicking Burkitt cells of Acute Lymphoid Leukemia-L3 (ALL-L3). Bone marrow aspirate revealed few mature myeloma cells for which a diagnosis of PCL was thought of. Serum electrophoresis showed a positive M-band and X-ray revealed lytic lesions over femur & pelvic bones. A final diagnosis of PCL was given.